Mark 10:6
But from the beginning of creation God made mankind male and female.
2 Peter 3:4
"Why has the promise of a coming Messiah [not been fulfilled yet]? After all, since the time our ancestors died, everything has continued the same, even since the beginning of creation!"
Mark 13:19
There will be great trouble during those days, such as had never been from the beginning of God's creation until the present, or even will be [in the days to come].
Treasury of Scripture Knowledge
Summary
But from the beginning of the creation God made them male and female.
The beginning
Bible References
The beginning
2 Peter 3:4
"Why has the promise of a coming Messiah [not been fulfilled yet]? After all, since the time our ancestors died, everything has continued the same, even since the beginning of creation!"