'Afflicted' in the Bible

After they had moved it, the Lord’s hand was against the city of Gath, causing a great panic. He afflicted the men of the city, from the youngest to the oldest, with an outbreak of tumors.

The men who did not die were afflicted with tumors, and the outcry of the city went up to heaven.

Why harden your hearts as the Egyptians and Pharaoh hardened theirs? When He afflicted them, didn’t they send Israel away, and Israel left?