'Afflicted' in the Bible

And Elkanah her husband saith to her, 'Hannah, why weepest thou? and why dost thou not eat? and why is thy heart afflicted? am I not better to thee than ten sons?'

After they had moved it, the Lord’s hand was against the city of Gath, causing a great panic. He afflicted the men of the city, from the youngest to the oldest, with an outbreak of tumors.

The men who did not die were afflicted with tumors, and the outcry of the city went up to heaven.

They inquired, "What is the guilt offering that we should send to him?" They replied, "The Philistine leaders number five. So send five gold sores and five gold mice, for it is the same plague that has afflicted both you and your leaders.

Why harden your hearts as the Egyptians and Pharaoh hardened theirs? When He afflicted them, didn’t they send Israel away, and Israel left?