'Against' in the Bible

Let no one in any way deceive you, for that day cannot come without the coming of the apostasy first, and the appearing of the man of sin, the son of perdition, who sets himself against,

who opposes and exalts himself on high against all called God, or object of veneration; so that he himself sits down in the temple of God, shewing himself that he is God.

For the mystery of lawlessness [rebellion against divine authority and the coming reign of lawlessness] is already at work; [but it is restrained] only until he who now restrains it is taken out of the way.

and with every kind of evil deception directed against those who are perishing, because they found no place in their hearts for the truth so as to be saved.