'Appointed' in the Bible

So the Lord said to him, “Therefore whoever kills Cain, vengeance will be taken on him sevenfold.” And the Lord appointed a sign for Cain, so that no one finding him would slay him.

Adam had relations with his wife again; and she gave birth to a son, and named him Seth, for, she said, “God has appointed me another offspring in place of Abel, for Cain killed him.”

Is anything too difficult for the Lord? At the appointed time I will return to you, at this time next year, and Sarah will have a son.”

So Sarah conceived and bore a son to Abraham in his old age, at the appointed time of which God had spoken to him.

now may it be that the girl to whom I say, ‘Please let down your jar so that I may drink,’ and who answers, ‘Drink, and I will water your camels also’—may she be the one whom You have appointed for Your servant Isaac; and by this I will know that You have shown lovingkindness to my master.”

and she will say to me, “You drink, and I will draw for your camels also”; let her be the woman whom the Lord has appointed for my master’s son.’