'Affliction' in the Bible

Now there came a dearth over all the land of Egypt and Chanaan, and great affliction: and our fathers found no sustenance.

I have seen, I have seen the affliction of my people which is in Egypt, and I have heard their groaning, and am come down to deliver them. And now come, I will send thee into Egypt.

serving the Lord with all humility and with tears and trials which came on me because of the plots of the Jews [against me];