'Trouble' in the Bible

So my mind was turned to grief for all the trouble I had taken and all my wisdom under the sun.

One hand full of rest is better than two hands full of trouble and desire for wind.

All his days are in the dark, and he has much sorrow, pain, disease, and trouble.

So put away trouble from your heart, and sorrow from your flesh; because the early years and the best years are to no purpose.