'Course' in the Bible

In the course of time Cain presented some of the land’s produce as an offering to the Lord.

And the waters retired from the earth, continually retiring; and in the course of a hundred and fifty days the waters abated.

Your descendants will return here in the fourth generation, since the iniquity of the Amorites has not yet run its course."

{And in the course of time} the daughter of Shua, the wife of Judah, died. When Judah was consoled he went up to his sheepshearers, he and his friend Hirah the Adullamite, to Timnah.

Now [in the course of time] there was no food in all the land, for the famine was distressingly severe, so that the land of Egypt and all the land of Canaan languished [in destitution and starvation] because of the famine.