'Effect' in the Bible

Therefore, since [these His] children share in flesh and blood [the physical nature of mankind], He Himself in a similar manner also shared in the same [physical nature, but without sin], so that through [experiencing] death He might make powerless (ineffective, impotent) him who had the power of death—that is, the devil—

for a will and testament takes effect [only] at death, since it is never in force as long as the one who made it is alive.