'Issue' in the Bible

And, behold, a woman, which was diseased with an issue of blood twelve years, came behind him, and touched the hem of his garment:

Now there were with us seven brethren: and the first, when he had married a wife, deceased, and, having no issue, left his wife unto his brother:

And Peter kept following Him at a distance, till he came even to the court of the High Priest's palace, where he entered and sat down among the officers to see the issue.