'Alienated' in the Bible

You see and hear that not only at Ephesus, but almost all over [the province of] Asia, this Paul has persuaded [people to believe his teaching] and has misled a large number of people, claiming that gods made by [human] hands are not really gods at all.

for their [moral] understanding is darkened and their reasoning is clouded; [they are] alienated and self-banished from the life of God [with no share in it; this is] because of the [willful] ignorance and spiritual blindness that is [deep-seated] within them, because of the hardness and insensitivity of their heart.

And although you were at one time estranged and alienated and hostile-minded [toward Him], participating in evil things,