'Bitter' in the Bible

"Why does he give light to one in misery and life to [those] bitter of soul,

"Indeed, you write bitter things against me, and you make me reap the iniquities of my childhood.

Yet another dies with a bitter inner self and has not tasted prosperity.

"Even today my complaint [is] bitter; my hand is heavy in addition to my groaning.

"{As God lives}, he has removed my justice, and Shaddai has made my inner self bitter.