'Despair' in the Bible

For we do not wish you to be ignorant, brethren, as to our tribulation which happened to us in Asia, that we were excessively pressed beyond our power, so as to despair even of living.

so that now instead you should rather forgive and comfort him. This will keep him from being overwhelmed by excessive grief to the point of despair.

We are troubled on every side, yet not distressed; we are perplexed, but not in despair;

Therefore we do not despair, but even if our physical body is wearing away, our inner person is being renewed day by day.