'Estranged' in the Bible

remember that at that time you were separated from Christ [excluded from any relationship with Him], alienated from the commonwealth of Israel, and strangers to the covenants of promise [with no share in the sacred Messianic promise and without knowledge of God’s agreements], having no hope [in His promise] and [living] in the world without God.

for their [moral] understanding is darkened and their reasoning is clouded; [they are] alienated and self-banished from the life of God [with no share in it; this is] because of the [willful] ignorance and spiritual blindness that is [deep-seated] within them, because of the hardness and insensitivity of their heart.