'Bitter' in the Bible

"A voice was heard in Ramah, wailing and bitter lamentation: It was Rachel bewailing her children, and she refused to be comforted because there were no more."

And they were bitter against him. But Jesus said to them, A prophet is nowhere without honour but in his country and among his family.

For out of the heart come evil thoughts, the taking of life, broken faith between the married, unclean desires of the flesh, taking of property, false witness, bitter words:

They gave him wine mixed with bitter drink: and after tasting it, he took no more.

And those who went by said bitter words to him, shaking their heads and saying,

And straight away one of them went quickly, and took a sponge, and made it full of bitter wine, and put it on a rod and gave him drink.