[This letter is from] Paul, an apostle of Christ Jesus by God's will, and [from] our brother Timothy,

[This will happen] if you continue in the faith [Note: This means either "continue to observe God's teaching" or, "continue to believe"], firmly grounded and established, and not moved away from the hope offered by the Gospel message, which you have heard and which was preached to people throughout the entire created world under heaven. I, Paul, was made a minister of this Gospel.

I want you to know how much I am struggling for you [Note: This probably refers to the great effort Paul was exerting in prayer, preaching, etc.], and for those at Laodicia [Note: This was a town ten miles west of Colosse], and for all those who have never met me in person.

This greeting [is being written] by me, Paul, in my own handwriting. Remember my imprisonment. [Note: This was probably a request for them to pray for him]. May God's favor be with you.