While the sun was setting [marking the end of the Sabbath day], all those who had any who were sick with various diseases brought them to Jesus; and laying His hands on each one of them, He was healing them [exhibiting His authority as Messiah].

So with many other appeals and various admonitions John preached the good news (gospel) to the people.

There will be violent earthquakes, and in various places famines and [deadly and devastating] pestilences (plagues, epidemics); and there will be terrible sights and great signs from heaven.

And he replied, “You shall love the Lord your God with all your heart, and with all your soul, and with all your strength, and with all your mind; and your neighbor as yourself.”