on account of which cause I indeed suffer these things: but I am not ashamed; for I know whom I have believed, and am persuaded that he is able to stand guard over that which is committed unto me unto that day.

stand guard over the beautiful deposit through the Holy Ghost who dwells in us.

For this reason I [am ready to] patiently endure all things for the sake of those who are the elect (God’s chosen ones), so that they too may obtain the salvation which is in Christ Jesus and with it the reward of eternal glory.

and the profane vain talkings stand aloof from, for to more impiety they will advance,

Nevertheless, the firm foundation of God [which He has laid] stands [sure and unshaken despite attacks], bearing this seal: “The Lord knows those who are His,” and, “Let everyone who names the name of the Lord stand apart from wickedness and withdraw from wrongdoing.”

and, even as Jannes and Jambres stood against Moses, so also these do stand against the truth, men corrupted in mind, disapproved concerning the faith;

Indeed, all who delight in pursuing righteousness and are determined to live godly lives in Christ Jesus will be hunted and persecuted [because of their faith].

You, however, must stand by what you learnt and accepted as true. You know who they were from whom you learnt it;

preach the word [as an official messenger]; be ready when the time is right and even when it is not [keep your sense of urgency, whether the opportunity seems favorable or unfavorable, whether convenient or inconvenient, whether welcome or unwelcome]; correct [those who err in doctrine or behavior], warn [those who sin], exhort and encourage [those who are growing toward spiritual maturity], with inexhaustible patience and [faithful] teaching.