The God who made the world and everything in it, who is Lord of heaven and earth, does not live in hand-made temples.

And now you have seen and heard, not only here in Ephesus, but throughout almost all of [the province of] Asia, that this Paul has been convincing people, [even] to the point of turning many away [from idol worship]. [He is] saying that hand-made gods [like we make] are not real [gods at all].

[It appears that] Alexander was appointed out of the crowd by the Jews [i.e., to be their spokesman in defending them from the charges being made against Paul]. He motioned with his hand [to get attention] and attempted to speak to the assembly in defense [of the Jewish viewpoint].