The Lord grant mercy to the family of Onesiphorus, because he often refreshed me and showed me kindness [comforting and reviving me like fresh air] and he was not ashamed of my chains [for Christ’s sake];

Paul, an apostle (special messenger, personally chosen representative) of Christ Jesus (the Messiah, the Anointed) by the will of God, according to the promise of life that is in Christ Jesus,

For this reason I [am ready to] patiently endure all things for the sake of those who are the elect (God’s chosen ones), so that they too may obtain the salvation which is in Christ Jesus and with it the reward of eternal glory.

and how from childhood you have known the sacred writings (Hebrew Scriptures) which are able to give you the wisdom that leads to salvation through faith which is in Christ Jesus [surrendering your entire self to Him and having absolute confidence in His wisdom, power and goodness].

The Lord be with your spirit. Grace be with you.